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. 2011 Aug 22;194(4):643–656. doi: 10.1083/jcb.201104124

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© 2011 Taguchi et al.

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Figure 7. — The effects of vinculin depletion on DLD1 cells. (A) Vinculin and EPLIN depletion causes fragmentation of E-cadherin signals. Vinculin remains to colocalize with E-cadherin in EPLIN-depleted cells, as indicated by arrows. (B) In vinculin-depleted and vinculin/EPLIN double-depleted cells, the fragmented E-cadherin signals no longer associate with tense actin fibers. (C) After vinculin depletion, E-cadherin no longer colocalizes with EPLIN. Bars, 10 µm.