Table 2.
All-cause mortality following hospitalization for acute HF in relation to weight status* in patients with diabetes, HR (95% CI)
| Underweight (n = 47) | Normal weight (n = 532) | Overweight (n = 479) | Class I obesity (n = 297) | Class II obesity (n = 136) | Class III obesity (n = 153) | |
|---|---|---|---|---|---|---|
| 1-year mortality | ||||||
| Cumulative incidence (%) | 72.3 | 49.1 | 42.2 | 32.7 | 24.3 | 40.5 |
| Crude | 1.8 (1.3 – 2.6) | (Referent) | 0.8 (0.7 – 1.0) | 0.6 (0.5 – 0.7) | 0.4 (0.3 – 0.6) | 0.8 (0.6 – 1.0) |
| Age-adjusted | 1.8 (1.2 – 2.5) | (Referent) | 0.9 (0.7 – 1.1) | 0.6 (0.5 – 0.8) | 0.5 (0.3 – 0.7) | 1.0 (0.7 – 1.3) |
| Multivariate-adjusted§ | 1.4 (1.0 – 2.0) | (Referent) | 0.9 (0.8 – 1.1) | 0.6 (0.5 – 0.8) | 0.5 (0.4 – 0.8) | 0.9 (0.7 – 1.3) |
| 5-year mortality | ||||||
| Cumulative incidence (%) | 100.0 | 87.2 | 82.5 | 80.1 | 70.6 | 78.4 |
| Crude | 1.9 (1.4 – 2.6) | (Referent) | 0.8 (0.7 – 0.9) | 0.7 (0.6 – 0.8) | 0.5 (0.4 – 0.7) | 0.7 (0.6 – 0.9) |
| Age-adjusted | 1.8 (1.4 – 2.5) | (Referent) | 0.9 (0.8 – 1.0) | 0.8 (0.6 – 0.9) | 0.6 (0.5 – 0.8) | 0.9 (0.7 – 1.1) |
| Multivariate-adjusted§ | 1.5 (1.1 – 2.0) | (Referent) | 0.9 (0.8 – 1.0) | 0.8 (0.6 – 0.9) | 0.6 (0.5 – 0.8) | 0.9 (0.8 – 1.2) |
*
Underweight (18.5 kg/m2 < body mass index [BMI]), normal weight (18.5 kg/m2 ≤ BMI < 25 kg/m2), overweight (25 kg/m2 ≤ BMI < 30 kg/m2), Class I obesity (30 kg/m2 ≤ BMI < 35 kg/m2), Class II obesity (35 kg/m2 ≤ BMI < 40 kg/m2), and Class III obesity (40 kg/m2 ≤ BMI).
All models adjusted for study cohort (1995 versus 2000).
§
Adjusted for study cohort (1995 versus 2000), age (categorical), sex, DNR, GFR (continuous), length of stay (continuous), history of hypertension, history of COPD, history of PVD, history of PCI, history of CABG, and history of atrial fibrillation.