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. Author manuscript; available in PMC: 2012 Aug 19.
Published in final edited form as: Mol Cell. 2011 Aug 19;43(4):515–527. doi: 10.1016/j.molcel.2011.06.024

Figure 6. Feedback-first regulation is conserved in the budding yeast S. bayanus.

Figure 6

Activation times are analyzed for all cell cycle regulated genes in a S. bayanus pheromone block-release microarray time-course (Guan, Dunham et al. 2010). (A) Intersection of cell cycle regulated genes in both budding yeasts. (B) Weak correlation between gene activation times in S. bayanus and S. cerevisiae for G1 block-release experiments. (C) Histogram of activation times of the cell cycle regulated genes in S. bayanus indicates that the G1 cyclins responsible for positive feedback, CLN1 and CLN2, are among the early-activated genes.