Skip to main content
. Author manuscript; available in PMC: 2011 Aug 24.
Published in final edited form as: Sci Transl Med. 2011 Jul 20;3(92):92ra66. doi: 10.1126/scitranslmed.3002543

Table 1.

Patient information. Correlations between mutations and clinical and histopathologic parameters of IPMNs.

N (total) KRAS mutation
P GNAS mutation
P
n % n %
Age (years) <65 29 22 75.9 0.42 18 62.1 0.62
≥65 103 85 82.5 69 67
Gender Male 70 58 82.9 0.58 51 72.9 0.07
Female 62 49 79 36 58.1
History of smoking Yes 25 21 84 0.77 17 68 0.85
No 37 30 81.1 26 70.3
Grade Low 23 20 87 0.43 (low versus others) 11 47.8 0.04 (low versus others)
Intermediate 51 46 90.2 34 66.7
High 58 41 70.7 42 72.4
Duct type Main 35 23 65.7 0.002 (main versus branch) 24 68.6 0.37 (main versus branch)
Branch 64 58 90.6 38 59.4
Mixed 28 21 75 20 71.4
Subtype Gastric 52 45 86.5 0.02 (pancreatobiliary versus intestinal) 34 65.4 0.002 (pancreatobiliary versus intestinal)
Pancreatobiliary 7 7 100 3 42.9
Intestinal 13 6 46.2 13 100
Diameter (cm) <3 62 49 79 0.58 41 66.1 0.96
≥3 70 58 82.9 46 65.7
Location Proximal (head) 77 64 83.1 0.44 (proximal versus distal) 53 68.8 0.38 (proximal versus distal)
Distal (body, tail) 49 38 77.6 30 61.2
Proximal and distal 6 5 83.3 4 66.7
Associated cancer Yes 24 18 75 0.4 18 75 0.3
No 108 89 82.4 69 63.9