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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Hypertension. 2011 Aug 1;58(3):446–453. doi: 10.1161/HYPERTENSIONAHA.111.177006

Figure 1.

Figure 1

Thrombin-induced increase in [Ca2+]i is dependent on NADPH oxidase. (A) Representative Fura-2 ratiometric images of [Ca2+]i showing inhibitory effects of DPI on thrombin-induced increase in [Ca2+]i in WT SMCs. (B) Summary data of thrombin-induced Ca2+ response in WT SMCs pretreated with vehicle (n=150 cells) or DPI (n=129 cells) followed by stimulation with thrombin. * P<0.05 vs. control; ‡ P<0.05 vs. vehicle + thrombin.