Skip to main content
. Author manuscript; available in PMC: 2012 Aug 5.
Published in final edited form as: Biochem Biophys Res Commun. 2011 Jun 25;411(3):490–495. doi: 10.1016/j.bbrc.2011.06.132

Figure 2.

Figure 2

2A. Dye transfer analysis by microinjection of Alexa 488 to test for GJIC in wild-type and CYPOR knock-down MG63 (upper panel) and wild-type and CYPOR knock-down 2T3 cells (lower panel). Increased dye transfer is seen in the wild-type cells compared to the CYPOR knock-down cells confirming the loss of gap junctions and GJIC in CYPOR knock-out cells.(* injected cell, representative images, n=12). 2B. Dye-uptake assay to test for hemichannel function in wild type and CYPOR knock-down 2T3 cells. CYPOR knock-down cells show decreased ethidium bromide uptake and hence decreased hemichannel function compared to the wild-type cells. (n=3)