Table 1.
Demographic and BA characteristics of patients with normal pulmonary function (N=679).
| Column (valid %) | ||
|---|---|---|
| Controller Naïve | On Controller Therapy | |
| No. Patients | N=510 (75%) | N=169 (25%) |
| Demographic Characteristics | ||
| Age at baseline (y) mean (SD) | 9.5 yrs (3.4) | 9.2 yrs (3.4) |
| 5–6 years | 125 (24.5%) | 48 (28.4%) |
| 7–9 years | 144 (28.2%) | 51 (30.2%) |
| 10–18 years | 241 (47.3%) | 70 (41.4%) |
| Age at asthma onset (y) | 4.4 yrs (4.1) | 4.0 yrs (3.1) |
| Gender: | ||
| Male | 291 (57.1%) | 106 (62.7%) |
| Female | 219 (42.9%) | 63 (37.3%) |
| Ethnicity: | ||
| Hispanic | 437 (85.7%) | 133 (78.7%) |
| Caucasian | 29 (5.7%) | 19 (11.2%) |
| Other | 44 (8.6%) | 17 (10.1%) |
| *BMI percentile: | ||
| Normal (<85%) | 223 (44.7%) | 86 (53.1%) |
| Overweight (85–94%) | 115 (23.0%) | 29 (17.9%) |
| Obese (>=95%) | 161 (32.3%) | 47 (29.0%) |
| BA Characteristics | ||
| Family History | 204 (40.0%) | 69 (40.8%) |
| Parental Smoking | 83 (17.9%) | 27 (17.6%) |
| Atopic(any + ST) a‡ | 315 (66.7%) | 118 (79.7%) |
| BDR mean (SD) | 5.9 (7.8) | 4.7 (7.1) |
| FEV1% -predicted ‡ | 100% (12.4) | 104% (13.4) |
| FEV1/FVC | 91% (6.1) | 92% (6.3) |
| FEF25–75%-predicted† | 101% (24.2) | 106% (25.7) |
| Impairment Factors: | ||
| Day Sx (>2 d/wk) | 252 (49.8%) | 96 (57.1%) |
| Night Sx (>2 nt/mos.) | 244 (48.4%) | 86 (51.2%) |
| Exercise limitations: | ||
| Sometimes | 156 (31.1%) | 53 (32.1%) |
| Usually | 176 (35.1%) | 55 (33.3%) |
| Beta2-agonist use (>2 d/wk) ‡ | 146 (29.0%) | 83 (49.4%) |
| School absenteeism (>=5 d) ‡ | 150 (29.4%) | 72 (42.6%) |
| Risk Factors (year prior): | ||
| Steroid Burst at Baseline Visit | 38 (7.5%) | 6 (3.6%) |
| Exacerbations (>=2) | 110 (21.6%) | 46 (27.2%) |
| ED visit/hospitalization (>=1) ‡ | 189 (37.1%) | 100 (59.2%) |
†
P≤.05,
‡
P≤.01 (Significance of distributional differences between controller therapy groups tested by chi-square test (categorical variables) and independent t-test (continuous variables).
a
Skin test performed in 88% of patients on therapy and 91% of controller naïve patients.
Skin tests: Cat, dog, feather, cockroach, mites, molds, weeds, trees, grass.
*
BMI: Body Mass Index