Table 1.
mRNA levels for genes related to myogenesis, chondrogenesis, and osteogenesis in vehicle- and BMP-2-treated tongues
| Genes | Vehicle | Recombinant BMP-2 | Significance |
|---|---|---|---|
| Myogenesis | |||
| MyoD | 0.0163 ± 0.00616 | 0.0172 ± 0.00467 | NS |
| Myogenin | 0.0256 ± 0.00510 | 0.0180 ± 0.00162 | p < 0.01 |
| MCK | 0.0661 ± 0.0149 | 0.0414 ± 0.00737 | p < 0.01 |
| Chondrogenesis, osteogenesis | |||
| Runx2 | 0 | 0.0000661 ± 0.0000800 | NS |
| Osteocalcin | 0.0000514 ± 0.0000552 | 0.0000581 ± 0.0000535 | NS |
| ALP | 0.000813 ± 0.000632 | 0.000700 ± 0.000576 | NS |
| Collagen II | 0.000167 ± 0.00246 | 0.000535 ± 0.0105 | NS |
| Collagen X | 0.000129 ± 0.00123 | 0.000155 ± 0.00168 | NS |
The mean ± standard deviation of six vehicle-treated or six BMP-2-treated tongues for each gene is shown. The ratio of each target gene mRNA relative to GAPDH mRNA is shown.