Table 2.
mRNA levels for genes related myogenesis, chondrogenesis, and osteogenesis in NTC- and BMP-2 siRNA-treated tongues
| Genes | NTC | BMP-2 siRNA | Significance |
|---|---|---|---|
| Myogenesis | |||
| MyoD | 0.0130 ± 0.00452 | 0.0136 ± 0.00515 | NS |
| Myogenin | 0.0128 ± 0.0044 | 0.0203 ± 0.0037 | p < 0.01 |
| MCK | 0.0646 ± 0.0251 | 0.116 ± 0.0275 | p < 0.01 |
| Chondrogenesis, osteogenesis | |||
| Runx2 | 0 | 0 | NS |
| Osteocalcin | 0.0000406 ± 0.0000632 | 0.0000356 ± 0.0000795 | NS |
| ALP | 0.00291 ± 0.00455 | 0.00365 ± 0.00460 | NS |
| Collagen II | 0.000202 ± 0.000333 | 0.0000435 ± 0.0000529 | NS |
| Collagen X | 0.000674 ± 0.000690 | 0.000264 ± 0.000265 | NS |
The mean ± standard deviation of six vehicle-treated or six BMP-2-treated tongues for each gene is shown. The ratio of each target gene mRNA relative to GAPDH mRNA is shown.