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. 2011 Aug 4;9:28. doi: 10.1186/1478-7954-9-28

Table 2.

Range of values for selected cause-specific and overall metrics of individual cause assignment and CSMF estimation for two different hypothetical VA assignment methods across 500 test datasets where the cause composition of the test datasets has been randomly varied.

Method 1 Method 2
Cause A Mean Median Max Min Mean Median Max Min

Sensitivity 0.70 0.70 0.70 0.70 0.80 0.80 0.80 0.80

Specificity 0.95 0.95 0.96 0.94 0.95 0.95 0.96 0.94

Absolute CSMF error 0.08 0.06 0.29 0.00 0.05 0.04 0.19 0.00

Relative CSMF error 0.74 0.24 53.38 0.00 0.71 0.15 53.48 0.00

Chance-corrected concordance 0.55 0.55 0.55 0.55 0.70 0.70 0.70 0.70

Estimated versus true regression Intercept Slope RMSE Intercept Slope RMSE

0.52 0.64 0.00 0.52 0.74 .00


Cause B Mean Median Max Min Mean Median Max Min

Sensitivity 0.60 0.60 0.60 0.60 0.60 0.60 0.60 0.60

Specificity 0.69 0.69 0.97 0.42 0.70 0.70 0.98 0.42

Absolute CSMF error 0.17 0.15 0.57 0.00 0.17 0.15 0.57 0.00

Relative CSMF error 4.50 0.37 229.07 0.00 4.43 0.37 228.56 0.00

Chance-corrected concordance 0.40 0.40 0.40 0.40 0.40 0.40 0.40 0.40

Estimated versus true regression Intercept Slope RMSE Intercept Slope RMSE

0.30 0.29 0.11 0.30 0.30 0.11


Cause C Mean Median Max Min Mean Median Max Min

Sensitivity 0.35 0.35 0.35 0.35 0.35 0.35 0.35 0.35

Specificity 0.69 0.69 0.73 0.64 0.73 0.73 0.82 0.64

Absolute CSMF error 0.20 0.19 0.63 0.00 0.19 0.17 0.63 0.00

Relative CSMF error 6.75 0.50 793.85 0.00 6.01 0.49 780.54 0.00

Chance-corrected concordance 0.03 0.03 0.03 0.02 0.03 0.03 0.03 0.02

Estimated versus true regression Intercept Slope RMSE Intercept Slope RMSE

0.31 0.03 0.01 0.26 0.08 0.03


Overall causes Mean Median Max Min Mean Median Max Min

Kappa 0.26 0.28 0.47 0.00 0.30 0.33 0.53 0.00

Total absolute CSMF error 0.46 0.45 1.26 0.01 0.42 0.37 1.26 0.03

CSMF accuracy 0.75 0.75 1.00 0.37 0.77 0.80 0.98 0.36