Table 3.
Performance of the verbal autopsy tool using HIV serostatus as gold standard, by age group
| Age group (years) | ||||
|---|---|---|---|---|
| 13-44 | 45-64 | 65+ | All ages | |
| Specificity (95% CI) | 76.5% (62.5-87.2%) | 90.0% (76.3-97.2%) | 96.5% (91.3-99.0%) | 90.2% (85.3-93.9%) |
| Positive predictive value (95% CI) | 72.7% (57.2-85.0%) | 77.8% (52.4-93.6%) | 33.3% (4.3-77.7%) | 70.6% (58.3-81.0%) |
| HIV-attributable mortality fraction (95% CI) | ||||
| this study | 50.6% (39.6-61.5%) | 30.5% (19.2-43.9%) | 5.1% (1.9-10.7%) | 25.8% (20.6-31.5%) |
| cohort (based on ALPHA data2) | 40.3% | 24.4% | 1.6% | 17.0% |
1Test (verbal autopsy) positive defined as positive by both assessors, or by 2 out of 3 assessors in case of nonagreement; test negative defined as negative or unknown by both assessors, or by 2 out of 3 assessors in case of nonagreement.
2Unpublished Analysing Longitudinal Population-based HIV cohorts in Africa (ALPHA) data