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Wild-type (solid line, n = 381 animals, 8 deaths), Npc1 mutants (○, n = 134 animals, 91 deaths), Npc2 mutants (□, n = 150 animals, 66 deaths) and Npc1/Npc2 double mutants (▪, n = 15 animals, 9 deaths) were in a BALB/c genetic background.
