Figure 8. Distribution of NPC1 and NPC2 in sucrose density gradients of ML differential fractions from wild-type mice.
NPC1 and NPC2 were quantitated by densitometry from data shown in Figs. 6 and 7. Also shown is the distribution of the lysosomal marker, β-galactosidase. A, liver; B, brain. Data are normalized to fraction of maximum value.