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. 2011 Aug 24;6(8):e23849. doi: 10.1371/journal.pone.0023849

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A. Examples of CDK1, PTTG1, Survivin and TOP2A subcellular staining in clinical tumor samples (-C: cytoplasmic staining; -N: nuclear staining). Staining is shown at 400× magnification. B. Tissue distribution of positive rates for CDK1, PTTG1, Survivin and TOP2A. AD: Adenocarcinoma; SCC: Squamous cell carcinoma; N-AD: Adjacent non-diseased lung tissues from Adenocarcinoma; N-SCC: Adjacent non-diseased lung tissues from squamous cell carcinoma; N-O: Non-pulmonary normal organs. C. Overview of entire tissue microarray staining for expression of these antigens in the cytoplasm or nucleus.