. Author manuscript; available in PMC: 2013 Jan 1.

Published in final edited form as: Pediatr Crit Care Med. 2012 Jan;13(1):53–59. doi: 10.1097/PCC.0b013e31821926bc

Table 3.

Acute adverse events during the 72 hours of cooling among infants with and without esophageal temperatures < 32°C

Adverse Events during 72 hours of treatment	No drops < 32°C (N=58)		Temp. < 32°C during induction or maintenance (N=43)		p-value (Fisher’s Exact Test)
Adverse Events during 72 hours of treatment	N	%	N	%	p-value (Fisher’s Exact Test)
Cardiac arrhythmia	2	3 %	0	0 %	0.51
Metabolic acidosis	1	2 %	1	2 %	1.00
Thrombosis	0	0 %	0	0 %	N/A
Bleeding	3	5 %	0	0 %	0.26
Alteration of skin integrity	3	5 %	1	2 %	0.63
Death	7	12 %	6	14 %	0.77
Any SAE	11	19 %	7	16 %	0.80