Skip to main content
. Author manuscript; available in PMC: 2012 May 24.
Published in final edited form as: Oncogene. 2011 May 23;30(47):4731–4739. doi: 10.1038/onc.2011.186

Figure 1. Sequence alignment of Isg20 and hPMC2.

Figure 1

The amino acid sequence of Isg20 was aligned with the C-terminus of hPMC2. Numbers indicate the amino acid positions, and gaps in the alignment are indicated by --. The two sequences were aligned using COBALT (Constraint-based Multiple Alignment Tool) from NCBI. The first line is the amino acid sequence of Isg20 while the next line indicates the sequence for hPMC2. Two conserved amino acids in hPMC2, (D247 and D386) enclosed by boxes are the residues that were mutated for the described studies.