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. 2011 May 21;36(10):1801–1808. doi: 10.1007/s11064-011-0497-z

Tabel 2.

The amount of metabolites in the brain tissue of hydrocephalus animals and controls

Control (n = 5) Hydrocephalus (n = 5) P-value
Glutathione 1.12 ± 0.16 1.02 ± 0.20 0.89
Aspartate 1.93 ± 0.20 1.69 ± 0.17 0.11
Glutamate 9.20 ± 0.50 7.86 ± 0.97* 0.03
Glutamine 5.90 ± 0.61 5.5 ± 0.51 0.15
GABA 0.96 ± 0.18 0.88 ± 0.04 0.33
Taurine 5.29 ± 0.63 4.54 ± 0.33* 0.04
Alanine 0.93 ± 0.07 0.69 ± 0.15* 0.02
NAA 11.73 ± 1.03 9.41 ± 1.76* 0.03
Myo-inositol 4.13 ± 0.55 4.12 ± 1.29 0.99
Lactate 4.58 ± 1.46 3.73 ± 1.80 0.43

All results are expressed as mean ± standard deviation of 5 control animals and 5 rats with hydrocephalus. All concentrations were corrected for wet weight (μmol/g tissue). Statistical differences between the two groups were analyzed using unpaired two-tailed Student’s t test

* The level of significance was set at P < 0.05