Table 4.

Frequencies of the alleles, genotypes and predicted phenotypes for the TNF-α -308 polymorphism according to CD behavior.

Variable	B1+p(Non-stricturing non-penetrating+perianal)	p-value*	B2+p(Stricturing+perianal)	p-value*	B3+p(Penetrating+perianal)	p-value*
Alleles	n = 124	0.003	n = 26	NS	n = 30	0.004**
G, n (%)	112(90.3)		21 (80.8)		20 (66.7)
A, n (%)	12(9.7)		5(19.2)		10(33.3)
Genotypes	n = 62		n = 13		n = 15
GG, n (%)	52 (83.9)		9 (69.2)		8 (53.3)
GA, n (%)	8(12.9)		3 (23.1)		4 (26.7)
AA, n (%)	2(3.2)		1 (7.7)		3 (20.0)
Predicted Phenotypes	n = 62	0.02	n = 13	NS	n = 15	0.02
Low Producer,n (%)	52 (83.8)		9 (69.2)		8 (53.3)
High Producer,n (%)	10 (16.2)		4 (30.8)		7 (46.7)

Number of alleles = 180; number of patients = 90.

^*Comparison with the other behaviors.

^*** Fisher's exact test.