Table 2.
Categories of rMED† |
Two-point increment in rMED‡ (11,994/15,049) |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Number of case subjects/number of subcohort* | Low (3,879/3,902) |
Medium (5,103/6,767) |
High (4,380/7,392) |
|||||||
HR§ | 95% CI | HR§ | 95% CI | HR§ | 95% CI | P (trend) | HR§ | 95% CI | P | |
Crude model | 1.00 | Referent | 0.74 | 0.70–0.79 | 0.65 | 0.60–0.71 | <0.001 | 0.88 | 0.86–0.90 | <0.001 |
Sex- and BMI-adjusted model | 1.00 | Referent | 0.87 | 0.81–0.94 | 0.80 | 0.72–0.89 | <0.001 | 0.94 | 0.91–0.96 | <0.001 |
Multiple adjusted model | 1.00 | Referent | 0.93 | 0.86–1.01 | 0.88 | 0.79–0.97 | 0.013 | 0.96 | 0.94–0.99 | 0.002 |
*Numbers in the subcohort exclude type 2 diabetic case subjects.
†rMED categories: low adherence to the MDP (rMED 0–6); medium adherence to the MDP (rMED 7–10); high adherence to the MDP (rMED 11–18).
‡rMED included as a continuous variable (range 0–18).
§Modified Cox proportional hazards regression models stratified by center. Multiple adjusted models were adjusted for sex, BMI (as continuous variable), educational level (no formal education, primary school, technical/professional school, secondary school, and longer education including university degree), physical activity (inactive, moderately inactive, moderately active, and active), smoking status (never, former, and three categories of current smoker: 1–10 cigarettes day−1, 11–20 cigarettes day−1, and >20 cigarettes day−1), and total calorie intake (as a continuous variable).