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Effect of electron transport inhibitors on NGF hyperalgesia. A. Rotenone, a mETC complex I inhibitor, attenuated NGF hyperalgesia at all time points. B. Oligomycin, a mETC complex V (ATP synthase) inhibitor, attenuated NGF hyperalgesia at all time points. N = 6 for all groups. Data are plotted as mean ± SEM. Significant differences between the groups are indicated by asterisks (*) plotted above the time points where they apply. Abbreviation: PWT = paw-withdrawal threshold.
