Table 3.
Time (min) | [11C]FP-TZTP(n=5) | [11C]P-TZTP (n=5) | [11C]F3P-TZTP (n=5) |
---|---|---|---|
1 | 92 ± 4 | 91 ± 5 | 95 ± 2 |
5 | 84 ± 5 | 83 ± 4 | 90 ± 4 |
10 | 64 ± 14 | 66 ± 9 | 84 ± 5 |
30 | 26 ± 8 | 32 ± 11 | 61 ± 14 |
60 | 20 ± 7 | 21 ± 5 | 48 ± 18 |
90 | 13 ± 3 | 12 ± 3 | 22 ± 2 |
There is no significant difference (p < 0.05) in % parent radiotracer between 11C-FP-TZTP and 11C-P-TZTP at any of the time points studied.
For 11C-F3P-TZTP the % parent radiotracer is significantly lower (p < 0.05) than for 11C-FP-TZTP and 11C-P-TZTP after 10 min.