Table 1.
Drug | No (%) of deaths
|
% change in incidence‡ (95% CI) | P value | % change in proportional incidence‡ (95% CI) | P value | ||
---|---|---|---|---|---|---|---|
Penultimate 12 months before change (n=2255) | 12 months before change (n=2234) | 12 months after change (n=2086)† | |||||
Paracetamol: | |||||||
Alone | 203 (9.0) | 185 (8.3) | 147 (7.0) | −21 (−34 to −5) | 0.01 | −18 (−33 to −1) | 0.04 |
With other drugs | 59 (2.6) | 56 (2.5) | 56 (2.7) | 2 (−26 to 39) | 0.9 | 5 (−24 to 44) | 0.8 |
Salicylates: | |||||||
Alone | 35 (1.6) | 29 (1.3) | 16 (0.8) | −48 (−70 to −11) | 0.02 | −46 (−69 to −7) | 0.03 |
With other drugs | 4 (0.2) | 8 (0.4) | 3 (0.1) | −48 (−85 to 81) | 0.3 | −46 (−85 to 91) | 0.3 |
Paracetamol and salicylates | 11 (0.5) | 5 (0.2) | 9 (0.4) | 18 (−47 to 163) | 0.7 | 21 (−47 to 174) | 0.6 |
16 September 1998.
These numbers were increased by 4.5% in the analyses. (See methods section for explanation.)
Comparison of 12 months after the change with the average of the two years before.