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. 2008 Sep 22;2:511–527. doi: 10.4137/cmo.s379

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© 2008 the author(s), publisher and licensee Libertas Academica Ltd.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license http://creativecommons.org/licenses/by/3.0/).

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(A) A dot plot representing the significant correlation between hTERT mRNA level in serum and that in gynecologic cancer tissues in 9 patients. Only a minority of the cases that were positive for mRNA in the tissue specimens (n = 8 for hTERT) is included in this analysis. Positive is defined as “being above the predictive cut-off values for both mRNAs obtained from this study in 89 lung tumors and 27 healthy individuals”. These data for hTERT mRNA were analyzed by Wilcoxon’s test and the paired t test (p < 0.028 and p = 0.035, respectively). The data are evaluated by a logarithm of quantification. (B) The quantification of both mRNAs in the serum before, during, and 7 days after any treatment including chemotherapy or surgical treatment is stratified into three groups. The data are evaluated by a logarithm of quantification. hTERT mRNA expression among the three groups was evaluated by the paired t test (*p < 0.05). N.S. means not significant.