Table 5.
Statistical analysis of the comparison between gynecologic tumor markers and clinical parameters.
| Clinical parameters | # of patients | Multivariate analysis
|
||
|---|---|---|---|---|
| hTERT mRNA
|
SCC
|
CA125
|
||
| p | p | p | ||
| Age mean: 55 years old (range 18 to 85 ) | <0.001 | N.S | 0.028 | |
| Etiology | ||||
| malignant | 89 | 0.004 | ||
| border | 3 | |||
| benign | 20 | |||
| Organ | ||||
| Uterus | 52 | N.S | ||
| cervical | 37 | |||
| body | 5 | 0.045 | N.S | N.S |
| Ovary | 39 | |||
| Others | 1 | |||
| Histological findings | ||||
| Uterus | N.S | 0.021 | N.S | |
| Squamous cell carcinoma | 29 | |||
| Endometrioid | 15 | |||
| Others | 22 | |||
| Ovary | 0.004 | N.S | <0.001 | |
| Serous | 24 | |||
| Mucinous | 9 | |||
| Others | 22 | |||
| Tumor size | 0.044 | N.S | N.S | |
| Tumor marker | ||||
| SCC(ng/ml) | N.S | N.S. | ||
| CA 125(mAU/ml) | 0.035 | N.S. | ||
| Staging | ||||
| 1 | 29 | <0.001 | 0.033 | 0.028 |
| 2 | 8 | |||
| 3 | 12 | |||
| 4 | ||||
| Before theraphy | 60 | N.S | N.S | 0.043 |
| During | 6 | |||
| After | 26 | |||
| Recurrence | ||||
| yes | 33 | N.S | N.S | N.S |
| no | 59 | |||