Table 2.

Quantitative analysis of BDNF–TrkB signaling and TrkB–NMDAR linkage in the hippocampus of sham- and rTMS-treated rats

	K–R	NMDA/glycine	K+	rhBDNF
SHAM
pY-TrkB 145 kDa/TrkB 145 kDa	0.13 ± 0.01	1.01 ± 0.07	1.09 ± 0.05	1.28 ± 0.09
pY-TrkB 95 kDa/TrkB 95 kDa	0.15 ± 0.02	0.82 ± 0.06	0.70 ± 0.04	0.89 ± 0.09
PLCγ1/TrkB 145 kDa	0.03 ± 0.01	0.69 ± 0.09	0.61 ± 0.08	0.81 ± 0.13
N-Shc/TrkB 145 kDa	0.14 ± 0.01	1.15 ± 0.11	1.04 ± 0.08	1.34 ± 0.11
Shc/TrkB 145 kDa	0.15 ± 0.01	1.63 ± 0.16	1.46 ± 0.16	1.90 ± 0.14
NR1/TrkB 145 kDa	0.23 ± 0.03	1.12 ± 0.06	0.96 ± 0.06	1.34 ± 0.07
NR2A/TrkB 145 kDa	0.18 ± 0.04	0.81 ± 0.03	0.62 ± 0.03	0.89 ± 0.05
PSD-95/TrkB 145 kDa	0.21 ± 0.03	1.19 ± 0.08	1.08 ± 0.08	1.37 ± 0.07
pY-ERK2/ERK2	0.21 ± 0.02	0.90 ± 0.05	0.92 ± 0.04	0.95 ± 0.04
pS473-Akt/Akt	0.07 ± 0.01	0.40 ± 0.04	0.35 ± 0.04	0.45 ± 0.02
rTMS
pY-TrkB 145 kDa/TrkB 145 kDa	0.15 ± 0.02	1.07 ± 0.08	1.11 ± 0.06	1.18 ± 0.10
pY-TrkB 95 kDa/TrkB 95 kDa	0.15 ± 0.02	0.86 ± 0.06	0.76 ± 0.05	0.90 ± 0.06
PLCγ1/TrkB 145 kDa	0.03 ± 0.01	0.70 ± 0.08	0.60 ± 0.06	0.80 ± 0.12
N-Shc/TrkB 145 kDa	0.14 ± 0.02	1.06 ± 0.07	0.98 ± 0.05	1.05 ± 0.06
Shc/TrkB 145 kDa	0.16 ± 0.02	1.68 ± 0.16	1.39 ± 0.13	1.53 ± 0.11
NR1/TrkB 145 kDa	0.24 ± 0.05	1.16 ± 0.10	0.98 ± 0.11	1.25 ± 0.10
NR2A/TrkB 145 kDa	0.16 ± 0.03	0.83 ± 0.04	0.68 ± 0.07	0.86 ± 0.05
PSD-95/TrkB 145 kDa	0.27 ± 0.04	1.25 ± 0.09	1.13 ± 0.08	1.28 ± 0.09
pY-ERK2/ERK2	0.18 ± 0.01	0.85 ± 0.05	0.75 ± 0.04	0.96 ± 0.05
pS473-Akt/Akt	0.07 ± 0.02	0.42 ± 0.03	0.41 ± 0.02	0.47 ± 0.03