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. 2011 Aug 22;6(8):e23847. doi: 10.1371/journal.pone.0023847

Table 1. Patient characteristics and clinicopathological variables and their prognostic value for disease-specific survival in 335 NSCLC patients (univariate analyses; log rank test).

Characteristic Patients(n) Patients(%) Median survival(months) 5-Year survival(%) P
Age
≤65 years 156 47 83 55 0.34
>65 years 179 53 NR 60
Sex
Female 82 25 190 63 0.20
Male 253 75 83 56
Smoking
Never 15 5 19 43 0.23
Current 215 64 NR 60
Former 105 31 71 54
Performance status
PS 0 197 59 NR 63 0.013
PS 1 120 36 64 52
PS 2 18 5 25 33
Weight loss
<10% 303 90 127 58 0.71
>10% 32 10 98 57
Histology
SCC 191 57 NR 66 0.08
AC 113 34 54 45
LCC 31 9 98 56
Differentiation
Poor 138 41 47 47 <0.001
Moderate 144 43 190 64
Well 53 16 NR 68
Surgical procedure
Lobectomy+Wedge* 243 73 190 61 0.004
Pneumonectomy 92 27 37 47
Pathological stage
I 157 47 190 71 <0.001
II 136 40 61 51
IIIa 42 13 17 23
Tumor status <0.001
1 85 25 190 74
2 188 56 84 57
3 62 19 25 36
Nodal status
0 232 69 190 66 <0.001
1 76 23 35 43
2 27 8 18 18
Surgical margins
Free 307 92 190 58 0.29
Not free 28 8 47 47
Vascular infiltration
No 284 85 190 58 <0.001
Yes 51 15 27 32

*Wedge, n = 10.

Abbreviations: NR = not reached; PS = Performance status; SCC = Squamous cell carcinoma, LCC = Large-cell carcinoma; AC = Adenocarcinoma (including bronchioloalveolar carcinoma).