Table 2. Expression of oxygen sensors in tumors as prognostic factors for disease-specific survival in 335 NSCLC patients (univariate analyses; log-rank test).
| Characteristics | Patients(n) | Patients (%) | Median survival (months) | 5-year survival (%) | P |
| PHD1 | 0.023 | ||||
| High | 150 | 45 | 71 | 53 | |
| Low | 171 | 51 | 190 | 65 | |
| Missing | 14 | 4 | |||
| PHD2 | 0.013 | ||||
| High | 258 | 77 | 83 | 55 | |
| Low | 68 | 20 | NR | 71 | |
| Missing | 9 | 3 | |||
| PHD3 | 0.018 | ||||
| High | 49 | 15 | 44 | 43 | |
| Low | 274 | 82 | 190 | 61 | |
| Missing | 12 | 3 | |||
| FIH | 0.033 | ||||
| High | 85 | 25 | 64 | 50 | |
| Low | 243 | 73 | NR | 60 | |
| Missing | 7 | 2 | |||
| Co-expression of oxygen sensors | <0.001 | ||||
| 0 | 36 | 11 | NR | 80 | |
| 1 | 106 | 32 | NR | 65 | |
| 2 | 112 | 33 | 190 | 57 | |
| 3 | 52 | 15 | 57 | 48 | |
| 4 | 10 | 3 | 24 | 23 | |
| Missing | 19 | 6 |