Skip to main content
. 2011 Aug 22;6(8):e23835. doi: 10.1371/journal.pone.0023835

Figure 5. The pharmacologically induced increase of intracellular Na+ activates caspase 3/7.

Figure 5

A) Total cell Na+ (blue trace) and K+ (red trace) levels in JH-EsoAd1 cells following incubation with 50 ng/ml amphotericin B (AMB) and 100 uM ouabain for 60 minutes (n = 6). The data are expressed as nmol ion/mg protein (*p<0.001 compared to control). B) Caspase-3/7 activity measured in JHEsoAD1 cells 24 hours following a 120 minute exposure to 50 ng/ml amphotericin B and 100 uM ouabain (*p<0.001 compared to control).