TABLE 3.
Ratio of Specific Signal for HABs, MABs, and LABs with Different TSPO Ligands
Ligand | LAB | MAB | HAB |
---|---|---|---|
PBR28 | 1 | 28.2 | 55.3 |
PBR06 | 1 | 9.2 | 17.3 |
DAA1106 | 1 | 2.9 | 4.7 |
PBR111 | 1 | 2.5 | 4.0 |
DPA173 | 1 | 2.7 | 4.4 |
PK11195 | 1 | 0.9 | 0.8 |
MABs are assumed to express equal number of HAB and MAB sites. Receptor density is assumed to remain constant. Values are calculated as BPND relative to BPND of LABs.