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. Author manuscript; available in PMC: 2011 Aug 25.
Published in final edited form as: Stat Med. 2010 Nov 30;30(7):709–717. doi: 10.1002/sim.4131

Table I.

Duality between the latent subgroup framework of MSLT-I and the all-or-none treatment noncompliance framework when controls have no access to active treatment.

Randomization MSLT-I
Noncompliance
Subgroup Treatment receipt Subgroup Treatment receipt
Treatment Node-positive Active treatment Complier Active treatment
Treatment Node-negative Control treatment Noncomplier Control treatment
Control ? Control treatment ? Control treatment

In MSLT-I, active treatment represents immediate lymphadenectomy, and the control treatment represents observational follow-up.