Table 1.
Pulmonary Characteristics and Body Composition between Patients and Controls
| Controls (n = 15) | Patients (n = 30) | P value | |
|---|---|---|---|
| Age, yr | 63.5 (5.7) | 66.0 (8.5) | 0.25 |
| Smoking pack-years, median (range) | 34.3 (10-80) | 53.3 (10-150) | 0.04 |
| Long acting β2 agonist n | 0 | 6 | |
| FEV1 (% predicted) | 92.9 (10.6) | 63.7 (17.9) | < 0.001 |
| FEV1(l) | 2.88 (0.48) | 1.95 (0.63) | < 0.001 |
| FVC (l) | 3.80 (0.71) | 3.41 (0.84) | 0.12 |
| O2 saturations at room air (%) | 96.3 (1.7) | 95.4 (1.7) | 0.08 |
| pO2 (kPA) | ND | 9.64 (1.5) | |
| ISWD (m) | 563 (221) | 424 (171) | 0.03 |
| BMI (kg/m2) | 29.7 (3.5) | 26.4 (5.1) | 0.03 |
| Total FFMI (kg/m2) | 20.4 (1.7) | 18.3 (2.4) | 0.004 |
| BMD Total Hip (g/cm2) | 1.05 (0.17) | 0.93 (0.14) | 0.01 |
| BMD Femoral neck (g/cm2) | 0.85 (0.14) | 0.74 (0.11) | 0.01 |
| BMD Total lumbar spine (g/cm2) | 1.13 (0.23) | 1.03 (0.20) | 0.11 |
Data presented as means (SD) unless stated otherwise
Definition of abbreviations: FEV1 = Forced expiratory volume 1 second, FVC = Forced vital capacity, RA = Room Air, ISWD = Incremental Shuttle Walk distance, BMI = Body Mass Index, BMD = Bone Mineral Density, FFMI = fat-free mass index, FMI = fat mass index, O2 = oxygen, ND = Not determined