Table 3.

Biochemistry and Markers of Bone Metabolism

	Controls (n = 15)	Patients (n = 30)	P value
25 OH Vitamin D (ug/l) #	16.1 (1.4)	11.4 (1.9)	0.03
PTH (pmol/l)#	6.71 (1.36)	6.12 (1.74)	0.58
Adjusted Calcium (mmol/l)	2.32 (0.09)	2.37 (0.11)	0.14
Creatinine (μmol/l)	100 (14)	95 (19)	0.36
Fasting glucose (mmol/l)	5.7 (0.7)	5.4 (0.6)	0.07
Testosterone (nmol/l)	13.9 (4.1)	14.8 (6.2)	0.62
T4 (pmol/l)	14.99 (1.97)	15.37 (2.47)	0.60
TSH (mU/l)	1.72 (0.91)	1.76 (0.81)	0.89
IL-6 (pg/ml) #	3.1 (2.2)	4.8 (2.8)	0.28
OPG (pmol/l) #	6.5 (1.9)	8.5 (1.4)	0.06
Osteocalcin (μg/l) #	23.0 (1.4)	22.7 (1.5)	0.93
P1NP (μg/l) #	40.9 (1.4)	45.6 (1.9)	0.47
CTX (μg/l) #	0.4 (1.5)	0.4 (1.9)	0.69

Data presented as mean (SD), unless # Geometric Mean (SD)

Definition of abbreviations:- PTH = parathyroid hormone, T4 = free thyroxine, TSH = thyroid stimulating hormone, IL-6 = Interleukin -6, OPG = osteoprotogerin, P1NP = Procollagen type 1 amino-terminal propeptide, βCTX = β-C-telopeptides of type I collagen