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. 2011 Aug 25;7(8):e1002140. doi: 10.1371/journal.pcbi.1002140

Figure 1. Schematic showing single cell bistability and population bimodal distribution.

Figure 1

For cCF10 pheromone (signaling molecule) induced pCF10 conjugation system, concentration of PrgB protein indicates the level of conjugation. Our model indicates that (A) due to different plasmid copy number in culture of cells, bimodal population distribution can arise from cells without bistability and (B) due to interaction with each other, cells with bistability can abandon bimodal population distribution.