Table 4.
Results of the fits to the Hodgkin data for the different dose-response models for carcinoma induction.
| Site | Linear (Eq.6) |
Full model (Eq.7) |
No fractionation (bell shape) R = 0 (Eq.9) |
Full tissue recovery (plateau) R = 1 (Eq.10) |
|||||
|---|---|---|---|---|---|---|---|---|---|
| β† | CV | α* | R | CV | α* | CV | α* | CV | |
| All solid | nc | 0.089 | 0.17 | 6.4E-3 | 0.065 | 4.8E-3 | 0.317 | 8.7E-4 | |
| Female breast | nc | 0.044 | 0.15 | 1.1E-5 | 0.041 | 8.6E-4 | 0.115 | 1.9E-3 | |
| Lung | nc | 0.042 | 0.83 | 2.0E-5 | 0.022 | 1.2E-2 | 0.056 | 1.7E-3 | |
| Rectum | nc | nc | 8.7E-1 | nc | 8.7E-1 | nc | 8.7E-1 | ||
| Colon | 7.2 | 1.8E-4 | 0.001 | 0.99 | 7.1E-3 | 0.001 | 2.5E-2 | 0.001 | 2.0E-4 |
| Mouth and pharynx | nc | 0.043 | 0.97 | 3.8E-4 | 0.017 | 2.0E-3 | 0.045 | 6.6E-3 | |
| Esophagus | excluded | ||||||||
| Stomach | nc | 0.460 | 0.46 | 8.4E-6 | 0.111 | 4.7E-3 | nc | 1.4E0 | |
| Small Intestine | nc | 0.591 | 0.09 | 3.0E-5 | 0.480 | 2.9E-5 | nc | 3.2E0 | |
| Liver | 0.22 | 3.4E-3 | 0.323 | 0.29 | 2.6E-5 | 0.243 | 3.4E-5 | 0.798 | 4.5E-2 |
| Cervix | 1.9 | 5.4E-4 | nc | 6.2E-1 | nc | 6.2E-1 | nc | 6.2E-1 | |
| Bladder | nc | 0.219 | 0.06 | 1.9E-5 | 0.213 | 4.1E-4 | 0.633 | 1.0E-4 | |
| Skin | 1.1 | 2.5E-3 | nc | 5.8E-1 | nc | 5.9E-1 | nc | 5.8E-1 | |
| Brain and CNS | 0.44 | 9.8E-3 | 0.018 | 0.93 | 1.3E-4 | 0.009 | 4.8E-3 | 0.021 | 4.2E-3 |
| Thyroid | excluded | ||||||||
| Salivary Gland | nc | 0.087 | 0.23 | 3.4E-5 | 0.059 | 4.0E-3 | 0.282 | 2.2E-4 | |
The fitted variables β, α and R are listed for each organ and each model. In addition the coefficient of variation (CV) is given. A fit corresponding to a CV > 0.05 was denoted as not converging (nc).
* in Gy-1
† in (10,000 PY Gy)-1