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. 2011 Aug 25;7(8):e1002193. doi: 10.1371/journal.ppat.1002193

Figure 3. Profile of EBV BART miRNAs in normal and neoplastic tissue.

Figure 3

The data is expressed as average and standard deviation of the fraction that each miRNA constitutes of the total of all EBV miRNAs. A. The four tumor types tested. Blue – Hodgkin's disease (n = 3): yellow – Burkitt's lymphoma (n = 6): green - gastric carcinoma (n = 6): red - nasopharyngeal carcinoma (n = 6). B. Normal infected tissue. Grey – GCB (n = 5), black – MemB (n = 4). The y intercept is a conservative approximation to the sensitivity of the assay (this will vary according to the input number of infected cells). It represents the fraction for a miRNA present at 10 copies, the lower limit of sensitivity for detection of all the miRNAs [16]. N.B. The miRNAs are presented on the x-axis from left to right in the order that they appear in the viral genome (see Figure 1).