Table 2. Gene products up-regulated in susceptible breast, lung, and SAEC cell lines compared to non-susceptible cells.
| Common Genes Up-regulated in Breast & Lung Cells | % Gene Up- Regulation in Breast Cells | % Gene Up- Regulation in Lung Cells | Common Genes Up-regulated in Breast, Lung, SAEC | % Gene Up- Regulation in SAEC |
| SLC6A14* | 173.1415 | 61.90872 | SLC6A14** | 46.87437 |
| RAB25 * | 161.964 | 188.6348 | ||
| CDH1* | 131.1153 | 45.16778 | ||
| GPC4* | 103.9329 | 129.3733 | ||
| STEAP4* | 100.7787 | 109.9432 | STEAP4** | 64.64598 |
| TMPRSS11E* | 96.91898 | 118.1558 | TMPRSS11E** | 46.68319 |
| NCAM2* | 94.40557 | 43.07266 | ||
| CDH3* | 93.77679 | 123.3686 | ||
| FXYD3 | 86.12615 | 41.92274 | ||
| MUC1* | 75.34311 | 49.158 | MUC1** | 32.83022 |
| MME | 73.32612 | 82.94319 | ||
| ERBB3* | 72.10978 | 45.78744 | ERBB3** | 23.24152 |
| PCDHB8* | 70.45194 | 89.7596 | ||
| ST14* | 68.33217 | 106.8741 | ||
| GABRA3 | 65.42129 | 50.05689 | ||
| PRSS8 | 58.427 | 52.65615 | ||
| PCDHB4* | 57.51795 | 53.33358 | ||
| SLC16A14* | 55.81763 | 38.13178 | ||
| ANK3 | 51.61145 | 44.22223 | ||
| PVRL4 | 50.68993 | 38.80007 | PVRL4** | 27.6538 |
| MUC15* | 47.35872 | 60.32913 | MUC15** | 23.22254 |
| SYK | 47.19083 | 68.0141 | ||
| SCNN1A* | 47.04117 | 64.89888 | ||
| PCDH1* | 41.70316 | 41.02153 | PCDH1** | 22.85412 |
| FAP | 40.45849 | 38.08091 | ||
| OR8G5 | 40.37826 | 51.7274 | ||
| ANO1 | 38.69293 | 45.62884 | ANO1 | 40.30204 |
| MUC20* | 37.97506 | 45.12805 | MUC20** | 44.45975 |
| PROM2* | 37.844 | 50.14194 | ||
| SUSD4* | 37.46031 | 27.36689 | ||
| EPCAM* | 37.39759 | 116.3044 | ||
| FGFBP1* | 36.91295 | 38.48566 | ||
| EPHA1* | 35.75165 | 50.02149 | ||
| EPCAM * | 35.06523 | 95.96663 | ||
| ENPEP | 34.85825 | 77.82285 | ||
| IGSF9 | 34.23295 | 35.2908 | ||
| CHRM3 | 32.84461 | 47.77368 | ||
| PCDHB15 | 30.85493 | 45.72636 | ||
| CLDN7* | 29.9608 | 84.29241 | CLDN7** | 26.90155 |
| RAB19 | 28.47934 | 39.00469 | ||
| DSC2 | 27.83151 | 45.32287 | ||
| MMP16 | 27.7552 | 27.27076 | ||
| PSD4 | 26.42839 | 37.93089 | ||
| MAL2* | 25.88348 | 184.0902 | ||
| GJB5 | 25.58353 | 43.39558 | ||
| GPR81 | 25.39142 | 115.9613 | ||
| ADAP1 | 25.17025 | 43.49649 | ||
| VEPH1 | 24.12028 | 35.18223 | ||
| PCDHB13 | 23.84833 | 85.86242 |
See also Table S1.
*Primary screening of candidate receptors with cDNA expression vectors following comparison of lung and breast cancer cell lines0.
**Secondary screening of candidate receptors with cDNA expression vectors following comparison of lung, breast, and SAEC cell lines.