| (1) L (Iso) |
(alg) Converted to parameter with assumption L≈Ltot |
| (2) β1ARfree
|
(alg) Solved analytically using conservation of mass |
| (3) Gs |
(alg) Converted to parameter with assumption Gs≈Gtot |
| (4) β1ARtot |
(ode) Solved analytically using conservation of mass |
| (5) β1ARd |
(ode) Equation not reduced |
| (6) β1ARp |
(ode) Equation not reduced |
| (7)Gsαgtptot |
(ode) Equation not reduced |
| (8) Gsαgdp
|
(ode) Removed with assumption Gsagdp <<Gs |
| (9) Gsβγ |
(ode) Removed with assumption Gsβγ ≈ Gsαgtptot |
| (10) Gsαgtp
|
(alg) Converted to an explicit linear equation based on Gsαgtptot using conc. clamps |
| (11) Fsk |
(alg) Converted to parameter with assumption Fsk≈Fsktot |
| (12) AC |
(alg) Solved analytically using conservation of mass |
| (13) PDE |
(alg) Solved analytically using conservation of mass |
| (14) IBMX |
(alg) Converted to parameter with assumption IBMX≈IBMXtot |
| (15) cAMPtot |
(ode) Equation not reduced |
| (16) cAMPfree
|
(alg) Converted to an explicit power equation based on cAMPtot using conc. clamps |
| (17) PKA1 |
(alg) Converted to a Hill equation based on cAMPtot using conc. clamps |
| (18) PKA2 |
(alg) Converted to a Hill equation based on cAMPtot using conc. clamps |
| (19) PLBp |
(ode) Reduced to a Hill equation based on PKA1 using conc. clamps (4-var model only) |
| (20) Inhib1ptot |
(ode) Reduced to a Hill equation based on PKA1 using conc. clamps |
| (21) Inhib1p |
(alg) Converted to a Hill equation based on PKA1 using conc. clamps |
| (22) PP1 |
(alg) Analytically solved by rearranging parameters |
| (23) LCCap |
(ode) Reduced to a Hill equation based on PKA2 using conc. clamps |
| (24) LCCbp |
(ode) Reduced to a Hill equation based on PKA2 using conc. clamps |
| (25) TnIp |
(ode) Reduced to a Hill equation based on PKA1 using conc. clamps (4-var model only) |
