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. 2011 Aug 25;6(8):e23846. doi: 10.1371/journal.pone.0023846

Figure 2. Altered Complex III gene expression in matched normal and tumor human breast tumors.

Figure 2

A. UQCRFS1-Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1; UQCRH-Ubiquinol-cytochrome c reductase hinge protein; CYC1-Cytochrome c-1; UCRC-Ubiquinol-cytochrome c reductase subunit X.; UQCRQ-Ubiquinol-cytochrome c reductase subunit VII; UQCR-Ubiquinol-cytochrome c reductase subunit XI; CYTB-Cytochrome b; UQCRB-Ubiquinol-cytochrome c reductase binding protein; UQCRC1-Ubiquinol-cytochrome c reductase core protein I; UQCRC2-Ubiquinol-cytochrome c reductase core protein II. Actin serves as a loading control. Subunits labeled in green are located in the intermembrane space, subunits labeled in red are transmemebrane, and subunits labeled in blue are located in the matrix. B. Coregulation of UQCRFS1 and UQCRH expression in matched normal and tumor breast tissue. C. Quantitative RT-PCR analyses of UQCRFS1 expression in matched normal and tumor breast tissue.