Table 2b.
Vandetanib (ng/mL) | % Difference from control | |||||
---|---|---|---|---|---|---|
7 day | 15 day | 30 day | 40 day | 60 day | 90 day | |
Plasma | ||||||
2.0 | 1.9 | 4.7 | −1.6 | 4.0 | −4.8 | 0.7 |
2500 | 2.7 | 0.7 | 3.3 | 0.6 | 6.6 | −6.8 |
CSF | ||||||
0.30 | −3.3 | 6.7 | 5.3 | 2.7 | −2.6 | 4.5 |
40 | 9.2 | 8.4 | 7.8 | 8.6 | −3.0 | 5.2 |