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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jul 18;879(25):2561–2566. doi: 10.1016/j.jchromb.2011.07.012

Table 2b.

Stability of vandetanib in human plasma and CSF at −80 C.

Vandetanib (ng/mL) % Difference from control

7 day 15 day 30 day 40 day 60 day 90 day
Plasma
2.0 1.9 4.7 −1.6 4.0 −4.8 0.7
2500 2.7 0.7 3.3 0.6 6.6 −6.8
CSF
0.30 −3.3 6.7 5.3 2.7 −2.6 4.5
40 9.2 8.4 7.8 8.6 −3.0 5.2