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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jul 18;879(25):2561–2566. doi: 10.1016/j.jchromb.2011.07.012

Table 2c.

Stability of vandetanib in human plasma and CSF through 3 freeze-thaw cycles.

Vandetanib (ng/mL) % Difference from control
1st cycle 2nd cycle 3rd cycle
Plasma
2.0 −3.4 0.9 2.7
2500 1.3 −3.5 −1.9
CSF
0.25 7.7 0.5 4.5
40 0.8 0.7 2.2