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. Author manuscript; available in PMC: 2012 Oct 15.
Published in final edited form as: Biochem Pharmacol. 2011 Jun 12;82(8):883–890. doi: 10.1016/j.bcp.2011.06.010

Fig 2.

Fig 2

Effects of Nicotine on Delayed Match to Sample (DMTS) performance in monkeys. Fig 1A illustrates the dose-effect relationship (2-3 replicates per dose) in the DMTS task (averaged across delay) in 5 adult pigtail monkeys, 10 min after the intramuscular administration of nicotine. Each bar represents the mean percentage change from vehicle baseline ± SEM over 96 trials per session. Fig 2B illustrates the effects of the individualized (and replicated) optimum dose of nicotine on each delay in the DMTS. Fig 2C illustrates the effect of the optimum dose of nicotine DMTS accuracy when the test was administered 24 h after dosing. *= significantly different (p<0.05 compared) to vehicle baseline levels of DMTS accuracy.