Table 2.
Contrast | Location of region | Cluster Volume (cc) | Corrected p-value | Effect* (%) |
---|---|---|---|---|
Relapsers+Abstainers vs. LD | Right temporal (including insula), frontal lobe | 11.7 | 0.001 | −8.5 |
Abstainers vs. LD | (1) Left amygdala, head of hippocampus, entorhinal cortex, thalamus, adjacent WM | 11.7 | <0.001 | −9.5 |
(2) Right thalamus, right colliculi, adjacent WM | 4.9 | 0.016 | −11.4 | |
(3) Left orbitofrontal | 2.1 | 0.035 | +10.1 | |
Relapsers vs. LD | (4) Right middle temporal (including insula) | 15.7 | <0.001 | −9.1 |
(5) Right occipital | 6.0 | 0.031 | −12.6 | |
(6) Left superior corona radiata | 12.5 | 0.043 | −10.3 | |
Relapsers vs. Abstainers | (7) Left lateral orbitofrontal | 8.1 | <0.001 | −10.8 |
(8) Left fronto-temporo-parietal | 9.9 | 0.014 | −14.4 | |
(9) Right lateral orbitofrontal | 3.8 | 0.033 | −8.0 | |
(10) Left amygdala, head of hippocampus, entorhinal cortex | 3.6 | 0.115 | +9.1 |
negative numbers indicate % tissue loss in alcohol groups vs. LD or in Relapsers vs. Abstainers Numbers in parenthesis identify locations in Figure 1.