Figure 3. Plasmid damage assay.
The pET22b-lacZ DNA was isolated from wild type (Lanes 1–2) and ΔaidB (Lanes 3–4) E. coli strains grown in the absence (A) or in the presence of MNNG (5µg/ml) (B), MMS 0.04% (C), ENNG (5µg/ml) (D), digested (Lanes 2, 4) or not (Lanes 1, 3) with AlkA and AP Endo and subjected to agarose gel electrophoresis. Lane 5, 1 Kb DNA marker (NEB). OC: open circular; L: linear; SC: supercoiled.