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Chromosome segregation during mitosis.
(A) In order to segregate chromosomes properly, sister kinetochores must attach to microtubules emanating from opposite spindle poles (amphitelic kinetochore attachment). (B) Merotelic kinetochore attachment is an error in which a single kinetochore is attached to microtubules emanating from both spindle poles. During anaphase, a merotelically attached chromatid lags behind and its timely segregation is hindered.
