Table 1.
DDD values and typical dose ranges for commonly prescribed antidepressants7
| BNF section | Drug class | Drug name | WHO DDD value (mg) | Range of dosing described in BNF (mg) |
|---|---|---|---|---|
| 4.3.1 | Tricyclic antidepressants (TCADs) | Amitriptyline | 75 | 10–200 |
| Dothiepin | 150 | 50–225 | ||
| Lofepramine | 105 | 140–210 | ||
| Trazadone | 300 | 75–600 | ||
| 4.3.3 | Selective serotonin reuptake inhibitors (SSRIs) | Citalopram | 20 | 10–60 |
| Escitalopram | 10 | 5–20 | ||
| Fluoxetine | 20 | 20–60 | ||
| Paroxetine | 20 | 10–50 | ||
| Sertraline | 50 | 25–200 | ||
| 4.3.4 | Other antidepressants | Duloxetine | 60 | 60 |
| Mirtazepine | 30 | 15–45 | ||
| Venlafaxine | 100 | 75–375 | ||
BNF = British National Formulary. DDD = defined daily dose. WHO =World Health Organization.