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Effect of compounds 5 and 7 and the reference drugs, indomethacin and hydrocortisone, on the time-course of leukocyte infiltration measured as myeloperoxidase activity up to 48 h (● controls; ◼ 0.4 μmol/cm2 compound 5; ◻ 0.4 μmol/cm2 compound 7; ▲ 0.4 μmol/cm2 indomethacin; Δ 0.04 μmol/cm2 hydrocortisone); *p < 0.05 in the analysis of variance, as compared to controls. Each point represents the mean of the results from 10 mice.
