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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Neuropharmacology. 2010 Dec 23;60(4):561–571. doi: 10.1016/j.neuropharm.2010.12.022

Fig. 11.

Fig. 11

Effect of repeated ICV infusion of Ucn III on PPI (a) and startle amplitude (b). Values shown are means ± SEMs. For all groups, n = 6. The average of all prepulse intensities is shown as Percent Prepulse Inhibition. The average startle amplitude across all trials on which the startling stimulus was presented alone is shown as Startle Amplitude. Rats received an ICV infusion of either saline (5.0 µl) or mouse Ucn III (20.0 µg) once/day on each of 5 consecutive days. The rats were tested for PPI 2.5 hours after the ICV infusion on days 1, 3, and 5. (a) Ucn III did not affect PPI on any of the test days. (b) There was an overall decrease in startle amplitude due to Ucn III, which was clearly due to effects on day 5.