Contra-ischemic ISOI reveals that changes in cortical function are limited to the ischemic hemisphere. The initial dip and overshoot phases of the contra-ischemic whisker functional representation remain constant throughout experimentation. A, B, Group baseline is paired with postocclusion stimulus data. Means and SEs are provided for the area (left) and amplitude (right) of the contra-ischemic C2 initial dip (A) and overshoot (B) phases of whisker functional representation before and immediately after stimulation treatment. ANOVA confirmed that there were no differences before and after pMCAO occlusion for either the area (+0 h: F(1,6) = 0.0004, p > 0.05; +1 h: F(1,6) = 0.078, p > 0.05; +3 h: F(1,6) = 0.007, p > 0.05) and amplitude (+0 h: F(1,6) = 0.009, p > 0.05; +1 h: F(1,6) = 0.275, p > 0.05; +3 h: F(1,6) = 0.132, p > 0.05) of the initial dip, or the area (+0 h: F(1,6) = 0.044, p > 0.05; +1 h: F(1,6) = 0.215, p > 0.05; +3 h: F(1,6) = 1.252, p > 0.05) and amplitude (+0 h: F(1,6) = 0.027, p > 0.05; +1 h: F(1,6) = 0.729, p > 0.05; +3 h: F(1,6) = 0.912, p > 0.05) of the overshoot phase. FC, Fractional change.