Z-band alignment in myocytes from PI3K transgenic mice. Representative cross sections from ventricles of Ntg, caPI3K, and dnPI3K mice. Anti-αactinin (a–c) stains sarcomeric bands and Z-lines, phalloidin-FITC (d–f) stains contractile thin filaments, and DAPI (g–i) stains nuclei. j–l, merged images. Scale bar = 20 μm. n = 4 in each group.